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Nephrotic Syndrome

Na & water retention

Edema ( Starts periorbital; pitting ) (Include effusions , Ascites )

Proteins are lost (Proteinuria > 3g/ day)  leading to low protein (Hypoalbuminemia <30 g/L)

Hypertension may develop.

Renal failure may develop.

O for "Oil" Hyperlipidemia ( may develop xanthomata /xanthelasma)

Thrombosis and thromboembolic complications including renal vein thrombosis due

                                                                                    to increased coagulability.

Infection can be the cause. Also , their with Nephrotic Syndrome are prone to infection.

Cause of it? (e.g. features of diabetes, collagen vascular disease such as SLE )

Reference: Murray Longmore, Ian Wilkinson, Estee Torok . Oxford Handbook of Clinical Medicine, 5thEdition. Oxford, Oxford University Press, 2001, p258.

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